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(61) demonstrated that combined L-carnitine and nicotinamide riboside administration upregulated multiple metabolic and insulin signaling regulators ( Ppargc1b, Acox1 ), promoting mitochondrial oxidative phosphorylation and peripheral glucose uptake

Mitochondriathe suicide organelles

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In addition to building the blood-brain barrier and secreting neural trophic factors, astrocytes are also responsible for brain edema and inflammation response after ICH (Chen-Roetling et al., 2015)

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